ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0016.3-2 | Thyroid Hormone Action | ESPEYB16

3.2. Thyroid hormone signaling specifies cone subtypes in human retinal organoids

KC Eldred , SE Hadyniak , KA Hussey , B Brenerman , PW Zhang , X Chamling , VM Sluch , DS Welsbie , S Hattar , J Taylor , K Wahlin , DJ Zack , RJ Jr Johnston

To read the full abstract: Science. 2018;362(6411).Here, developmental regulation of deiodinases DIO2 and DIO3 were identified as main regulators of thyroid hormone dependent sequential cone subtype specification in human retinal organoids. Either complete loss of thyroid hormone signaling or non-physiologically high thyroid hormone levels completely suppressed either medium and long wav...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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