ESPE Yearbook of Paediatric Endocrinology

Brief summary: This study investigated adipose tissue cellularity and functionality in more than 400 individuals with early-onset obesity (before the age of 18 years) versus late-onset of obesity (after the age of 18 years) compared to never-obese subjects. Individuals with obesity had increased subcutaneous white adipose tissue amounts resulting from a combination of increased size and numbers of fat cells.Interestingly, individuals with early-onset obe...