ESPE Yearbook of Paediatric Endocrinology

Brief summary: This review article draws on existing studies of type 1 diabetes (T1D) in sub-Saharan Africa, examining differences in phenotype, genetic susceptibility and rates of autoimmunity within this population. Lack of large prospective studies with well-standardized methodologies are noted in this population, making more definitive studies necessary.This article reviews studies reporting the clinical features of patients with T1D in sub-Saharan A...

jcmbanya@yahoo.co.uk Pediatr Diabetes 2022; 23: 33–37. doi: 10.1111/pedi.13294Brief Summary: Despite provision of free insulin by the Changing Diabetes in Children (CDiC) program, mortality remains high in children and adolescents with type 1 diabetes (T1D) in Cameroon, in particular in rural settings and in families with no formal education.<p cl...

Brief Summary: This longitudinal study describes the long-term effects of prenatal alcohol exposure on early childhood development. The results clearly show that prenatal alcohol exposure impairs growth and IGF-1 levels in children, highlighting the need for public health interventions to prevent alcohol consumption during pregnancy, especially in low-resource settings.This study assessed the long-term consequences of prenatal alcohol exposure (PAE) on e...

In Brief: The authors highlight recent data published by the UK Office for Health Improvement and Disparities (OHID) on estimated excess mortality in England, overall and by age, ethnicity, region and cause. Age-standardised mortality was higher than expected during June 2022 to 30th June 2023. Particular causes of death showed excess mortality: cardiovascular diseases (12% relative excess), heart failure (20%), ischaemic heart diseases (15%), liver diseases (19%), acute respi...