ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0017.5-7 | Translational Highlights | ESPEYB17

5.7. RANKL Inhibition in fibrous dysplasia of bone: A preclinical study in a mouse model of the human disease

B Palmisano , E Spica , C Remoli , R Labella , A Di Filippo , S Donsante , F Bini , D Raimondo , F Marinozzi , A Boyde , P Robey , A Corsi , M Riminucci

To read the full abstract: J Bone Miner Res. 2019;34(12):2171–2182.In brief: The effect of RANKL inhibition on fibrous dysplasia development is explored here using a mouse model of a fibrous dysplasia-like disorder. Anti-mouse RANKL monoclonal antibody treatment prevented the development and growth of lesions. However, after discontinuation of anti-mouse ...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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