ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

Page 1 of about 2 results

ey0021.1-2 | New Mechanisms | ESPEYB21

1.2. Kisspeptin signalling in astrocytes modulates the reproductive axis

Torres E. , Pellegrino G. , Granados-Rodriguez M. , Fuentes-Fayos A.C. , Velasco I. , Coutteau-Robles A.

Brief Summary: This study uses a combination of proteomics and murine transgenics to identify the role of Kisspeptin signalling in astrocytes and how it impacts the reproductive axis.Kisspeptin, a neuropeptide, is essential for regulating the hypothalamic-pituitary-gonadal (HPG) axis, which controls reproduction by acting on GnRH neurons. While most studies have focused on GnRH neurons as the primary mediators of kisspeptin signalling and function, this ...
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ey0018.7-10 | Basic Science | ESPEYB18

7.10. Central ceramide signaling mediates obesity-induced precocious Puberty

V Heras , JM Castellano , D Fernandois , I Velasco , E Rodriguez-Vazquez , J Roa , MJ Vazquez , F Ruiz-Pino , M Rubio , R Pineda , E Torres , MS Avendano , A Paredes , L Pinilla , D Belsham , C Dieguez , F Gaytan , N Casals , M Lopez , M Tena-Sempere

Cell Metab. 2020 Dec 1;32(6):951–966.e8. 10.1016/j.cmet.2020.10.001. PMID: 33080217. https://www.sciencedirect.com/science/article/pii/S1550413120305349?via%3DihubIn brief: This study reveals the critical role of hypothalamic ceramide synthesis in the induction of precocious puberty in obe...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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