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15.15. Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior

A Ganna , KJH Verweij , MG Nivard , R Maier , R Wedow , AS Busch , A Abdellaoui , S Guo , JF Sathirapongsasuti , 23andMe Research Team , P Lichtenstein , S Lundstrom , N Langstrom , A Auton , KM Harris , GW Beecham , ER Martin , AR Sanders , JRB Perry , BM Neale , BP Zietsch

To read the full abstract: Science 2019;365:eaat7693.These authors performed a genome-wide association study on 493 001 participants of European-ancestry from the USA, UK, and Sweden to identify genes associated with sexual orientation. They found multiple loci implicated in same-sex sexual behavior indicating that, like other behavioral traits, non-heterosexual behavior is polygenic.As many as 4% to 10% of US individuals ...

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ey0016.9-6 | Metabolic and Cardiovascular Risk in Cancer Survivors | ESPEYB16

9.6. Late cardiovascular morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation

CN Duncan , R Brazauskas , J Huang , BE Shaw , NS Majhail , BN Savani , MED Flowers , M Battiwalla , K Beebe , AC Dietz , CC Dvorak , R Giller , DA Jacobsohn , M Kletzel , PL Martin , ER Nemecek , B Nuechterlein , JA Talano , MA Pulsipher , KS Baker

To read the full abstract: Bone Marrow Transplant. 2018 Oct; 53 (10):1278Early cardiovascular disease is relatively common among childhood cancer survivors (CCS). A high risk of accelerated atherosclerosis and a 8.2-fold higher cardiac mortality rate have been reported (1). Arterial stiffness, an independent risk factor for cardiovascular morbidity and mortality in adults, seems to incre...

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ESPE Yearbook of Paediatric Endocrinology

15.15. Large-scale GWAS reveals insights into the genetic architecture of same-sex sexual behavior

9.6. Late cardiovascular morbidity and mortality following pediatric allogeneic hematopoietic cell transplantation

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