ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0019.15-6 | New Hormones | ESPEYB19

15.6. A hormone complex of FABP4 and nucleoside kinases regulates islet function

KJ Prentice , J Saksi , LT Robertson , GY Lee , KE Inouye , K Eguchi , A Lee , O Cakici , E Otterbeck , P Cedillo , P Achenbach , AG Ziegler , ES Calay , F Engin , GS Hotamisligil

Nature. 2021;600(7890):720-6. doi: 10.1038/s41586-021-04137-3.PubMed ID: 34880500Brief summary: This mouse study identifies FABP4 (‘Fabkin’) as a new fat-derived hormone that regulates insulin-producing beta cells in the pancreas.We have learnt over the recent years that body fat is not simply a passive energy storage tissue, but instead secretes a number o...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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