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ey0019.11-7 | New findings in adipose tissue biology | ESPEYB19

11.7. Leptin resistance before and after obesity: evidence that tissue glucose uptake underlies adipocyte enlargement and liver steatosis/steatohepatitis in Zucker rats from early-life stages

MA Guzzardi , L Guiducci , D Campani , F La Rosa , A Cacciato Insilla , A Bartoli , M Cabiati , V De Sena , S Del Ry , S Burchielli , F Bonino , P Iozzo

patricia.iozzo@ifc.cnr.it Int J Obes (Lond) 2022, 46(1):5058. doi: 10.1038/s41366-021-00941-zBrief Summary: This experimental study was conducted with fa/fa rats that have a homozygous defect in the leptin receptor and therefore severe leptin resistance. The animals develop extreme obesity, diabetes and metabolic syndrome. The study of y...

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ESPE Yearbook of Paediatric Endocrinology

11.7. Leptin resistance before and after obesity: evidence that tissue glucose uptake underlies adipocyte enlargement and liver steatosis/steatohepatitis in Zucker rats from early-life stages

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