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ey0021.14-13 | Risk and Outcome | ESPEYB21

14.13. Influence of state-of-the-art laboratory techniques on the phenotyping of women with polycystic ovary syndrome in the clinical setting

Luque-Ramirez M. , Martinez-Garcia M. A. , Insenser M. , Fernandez-Duran E. , Quintero-Tobar A. , Fiers T. , Kaufman J-M. , Garcia-Cano A.M. , Coronado M. Rosillo , Nattero-Chavez L. , Escobar-Morreale H.F.

Brief Summary:This cross-sectional study investigated assay methods for diagnosing PCOS among 359 premenopausal women presenting with functional androgen excess or hyperandrogenemia. Serum androgens and AMH were measured by both immunoassay and LCMS/MS, and ovarian ultrasound was performed. Steroid immunoassays used in routine practice were unacceptably inaccurate compared to LC-MS/MS, and PCOS-positive serum AMH measurements were often not confirmed by ovari...

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ESPE Yearbook of Paediatric Endocrinology

14.13. Influence of state-of-the-art laboratory techniques on the phenotyping of women with polycystic ovary syndrome in the clinical setting

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