ESPE Yearbook of Paediatric Endocrinology

Preface: A PubMed search for “Medicine and Science” limited to the last 12 months will return 303 153 hits, and if filtered for reviews 38 153. These numbers change to 802 and 127, respectively, when the search is performed with the term “Science and Medicine”. This shows that it is exceedingly difficult to search for “the” most important articles to provide in this chapter. Thus we have taken a different approach, by asking members of the team of...

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Preface: In the last year the scientific community was again very active in research in both topics, differences/disorders of sex development (DSD) and transgender medicine.In DSD, next generation sequencing approaches revealed novel variants in genes so far not suspected to participate in sex development (e.g. MYRF, DHX37, PPP1R12A ). This expands the landscape of genes and proteins involved in DSD and provides further challenges for explaining...

Preface: Our PubMed search for DSD revealed close to 3000 articles and the search for transgender and gender dysphoria about 250 articles for the past 12 months. The topics in DSD were very broad ranging from new and old genes and their mechanism of action to diagnostic themes and new therapeutic options. Additional reports on gender dysphoria with DSD and articles on ethical discussions were published. In transgender, there were many articles on gender dysphoria and autism as...

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This year my team in Bern (Philipp Augsburger, Claudia Böttcher, Therina du Toit, Marco Janner, Chrysanthi Kouri, Idoia Martinez de LaPiscina, Rawda Na’Amneh Elzenaty, Anne Smit, Isabel Sousa Barata, Jibira Yakubu) and the YES member, Simge Eren, Şişli Hamidiye Etfal Training and Research Hospital, Pediatric Endocrinology Department, Istanbul participated in choosing the articles you will find in this Chapter....

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