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ey0017.11-9 | Body Weight Regulation and Insulin Sensitivity | ESPEYB17

11.9. Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity

AE O’Mara , JW Johnson , JD Linderman , RJ Brychta , S McGehee , LA Fletcher , YA Fink , D Kapuria , TM Cassimatis , N Kelsey , C Cero , ZA Sater , F Piccinini , AS Baskin , BP Leitner , H Cai , CM Millo , W Dieckmann , M Walter , NB Javitt , Y Rotman , PJ Walter , M Ader , RN Bergman , P Herscovitch , KY Chen , AM Cypess

To read the full abstract: J Clin Invest. 2020;130(5):22092219. doi: https://pubmed.ncbi.nlm.nih.gov/31961826/This clinical study addressed the chronic effects of the β3-adrenergic receptor agonist mirabegron on BAT activity, blood parameters, and insulin sensitivity in a small cohort of healthy women (n =14). Participants were treated for 4 weeks orally with mirabegron ...

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ey0021.15-8 | New Concerns | ESPEYB21

15.8. Causes and consequences of child growth faltering in low-resource settings

A Mertens , J Benjamin-Chung , JM, Jr. Colford , J Coyle , MJ van der Laan , AE Hubbard , S Rosete , I Malenica , N Hejazi , O Sofrygin , W Cai , H Li , A Nguyen , NN Pokpongkiat , S Djajadi , A Seth , E Jung , EO Chung , W Jilek , V Subramoney , R Hafen , J Haggstrom , T Norman , KH Brown , P Christian , BF Arnold , The Ki Child Growth Consortium.

In Brief: The authors perform a population intervention effects analysis of 33 longitudinal cohorts (total 83 671 children, 662 763 measurements), from 15 low- and middle-income counties (LMICs). They estimate that improving maternal anthropometry and child condition at birth would increase population mean length-for-age z-scores by up to 0.40 and weight-for-length z -scores by up to 0.15 by 24 months of age.This is 1 of 3 full articles publishe...

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ESPE Yearbook of Paediatric Endocrinology

11.9. Chronic mirabegron treatment increases human brown fat, HDL cholesterol, and insulin sensitivity

15.8. Causes and consequences of child growth faltering in low-resource settings

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