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ey0015.9-7 | Growth, growth hormone and puberty in chronic diseases: novel insights from clinical practice | ESPEYB15

9.7 Growth outcomes after GH therapy of patients given long-term corticosteroids for Juvenile Idiopathic Arthritis

H David , C Aupiais , B Louveau , P Quartier , E Jacqz-Aigrain , JC Carel , D Simon

To read the full abstract: J Clin Endocrinol Metab. 2017;102:4578-4587In chronic inflammatory diseases, inflammatory cytokines and exogenous glucocorticoid exposure affect growth through systemic effects on the GH–IGF-1 axis and local effects on the growth plates. Low plasma IGF-1 levels are related to systemic GH insufficiency or to hepatic GH resistance. Changes in IGF binding proteins ha...

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ESPE Yearbook of Paediatric Endocrinology

9.7 Growth outcomes after GH therapy of patients given long-term corticosteroids for Juvenile Idiopathic Arthritis

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