ISSN 1662-4009 (online)

ey0017.7-2 | Clinical Guidance | ESPEYB17

7.2. Sex-specific estrogen levels and reference intervals from infancy to late adulthood determined by LC-MS/MS

H Frederiksen , TH Johannsen , SE Andersen , J Albrethsen , SK Landersoe , JH Petersen , AN Andersen , ET Vestergaard , ME Schorring , A Linneberg , KM Main , AM Andersson , A Juul

To read the full abstract: Journal of clinical endocrinology and metabolism vol. 105,3 (2020):754–768. doi: https://academic.oup.com/jcem/article/105/3/754/5624050The authors used state-of-the-art liquid chromatography tandem mass spectrometry to establish sex-specific reference ranges for estrone (E1) and estradiol (E2) throughout life and evaluate sex-differences.</...

ey0016.2-16 | Fetal and Neonatal Cortisol Physiology | ESPEYB16

2.16. Characterization of human adrenal steroidogenesis during fetal development

C Melau , JE Nielsen , H Frederiksen , K Kilcoyne , S Perlman , L Lundvall , LL Thuesen , K Juul Hare , AM Andersson , RT Mitchell , A Juul , A Jorgensen

J Clin Endocrinol Metab. 2018 Dec 21. [Epub ahead of print]. doi: 10.1210/jc.2018-01759.This study aimed to investigate Human fetal adrenal (HFA) steroidogenesis by analyzing adrenal glands from 1st and 2nd trimester. Steroidogenesis in the HFA is tightly regulated throughout the first and second trimesters, which is crucial because the adrenal steroid hormones affect the overall intrauterine endocri...