ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Endocrinology 2019;160:557–567.There is now no doubt that arcuate nucleus (ARC) kisspeptin neurons are the GnRH pulse generator. The authors analyzed the activity of ARC kisspeptin neurons by using a very powerful method based on the recording of calcium concentration within cells.ARC kisspeptin neurons activity was analyzed in male ...

To read the full abstract: Endocrinology 2019;160:1480–1491.There is now no doubt that arcuate nucleus (ARC) kisspeptin neurons are the GnRH pulse generator. (With paper 1.8) this second paper describes the activity of the GnRH pulse generator across the estrous cycle. In this work, the variable level of E2 represented an additional complexity. The second interest was to understand ...