ey0018.2-6 | Neonatal hypoglycaemia | ESPEYB18
S Tornovsky-Babeay
, N Weinberg-Corem
, R Ben-Haroush Schyr
, D Avrahami
, J Lavi
, E Feleke
, KH Kaestner
, Y Dor
, B Glaser
Diabetologia. 2021 May;64(5):1133-1143. doi: 10.1007/s00125-021-05390-x. PMID: 33558985.In order to gain some insight into the potential mechanism/s of diminished beta cell function over time, this mouse model of CHI was developed with an activating GCK (Glucokinase) mutation. In the short term, the mice developed mild fasting hypoglycaemia (this was very mild with fasting blood glucose...