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10.8. Absence of islet autoantibodies and modestly raised glucose values at diabetes diagnosis should Lead to testing for MODY: lessons from a 5-year pediatric Swedish National Cohort study

A Carlsson , M Shepherd , S Ellard , M Weedon , A Lernmark , G Forsander , K Colclough , Q Brahimi , C Valtonen-Andre , SA Ivarsson , H Elding Larsson , U Samuelsson , E Ortqvist , L Groop , J Ludvigsson , C Marcus , AT Hattersley

Diabetes Care. 2020; 43:8289. doi: 10.2337/dc19-0747.It is often difficult to identify maturity-onset diabetes of the young (MODY) in pediatric patients close to diabetes onset. Hence, misdiagnosis and unnecessary insulin treatment are still common.This study reports the discriminatory clinical features at diabetes onset in Swedish pediatric patients (age 118 y...

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ey0015.10-20 | Prevention | ESPEYB15

10.20 Effect of hydrolyzed infant formula vs conventional formula on risk of T1DM. The TRIGR randomized clinical trial

Writing Group for the TRIGR Study Group , M Knip , HK Åkerblom , E Al Taji , D Becker , J Bruining , L Castano , T Danne , C de Beaufort , HM Dosch , J Dupre , WD Fraser , N Howard , J Ilonen , D Konrad , O Kordonouri , JP Krischer , ML Lawson , J Ludvigsson , L Madacsy , JL Mahon , A Ormisson , JP Palmer , P Pozzilli , E Savilahti , M Serrano-Rios , M Songini , S Taback , Vaarala , NH White , SM Virtanen , R Wasikowa

To read the full abstract: JAMA. 2018;319:38-48Earlier observational studies showed that dietary exposure to complex proteins in newborns and early infants is associated with beta cell autoimmunity and increase the risk for T1DM. Several studies avoiding certain proteins, such as gluten and casein, have been conducted without reducing the risk for T1D in genetically susceptible children. Theref...

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ESPE Yearbook of Paediatric Endocrinology

10.8. Absence of islet autoantibodies and modestly raised glucose values at diabetes diagnosis should Lead to testing for MODY: lessons from a 5-year pediatric Swedish National Cohort study

10.20 Effect of hydrolyzed infant formula vs conventional formula on risk of T1DM. The TRIGR randomized clinical trial

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