ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

Page 1 of about 2 results

ey0017.2-19 | Maternal Obesity and Long-Term Infant Consequences | ESPEYB17

2.19. Prolonged prepregnant maternal high-fat feeding reduces fetal and neonatal blood glucose concentrations by enhancing fetal [beta]-cell development in C57BL/6 mice

L Qiao , JS Wattez , L Lim , PJ Rozance , WW Jr Hay , J Shao

To read the full abstract: Diabetes. 2019 Aug;68(8):1604–1613. doi: 10.2337/db18-1308. Epub 2019 May 24. PMID: 31127056Maternal obesity is an important risk factor for neonatal hypoglycaemia. Maternal BMI predicts the risk of neonatal hypoglycaemia independently from maternal obesity suggesting that the link between maternal adiposity and neonatal hypoglycaemia is complex. Identifying the u...
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ey0020.13-4 | Section | ESPEYB20

13.4. Evolution of the germline mutation rate across vertebrates

LA Bergeron , S Besenbacher , J Zheng , P Li , MF Bertelsen , B Quintard , JI Hoffman , Z Li , J St Leger , C Shao , J Stiller , MTP Gilbert , MH Schierup , G Zhang

In Brief: The authors conducted genome sequencing on 151 mother–father–offspring trios from 68 vertebrate animal species in order to estimate and compare germline mutation rates (GMRs). They found a 40-fold variation in GMR per generation between the species. Higher GMRs were observed in species that have a longer generation time, older age at puberty and fewer offspring per generation.Comment: Mutations in germline DNA during gametogenesis are...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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