ey0021.11-9 | Genetic Risk Score and New Genes | ESPEYB21
TJ Renier
, D Yeum
, JA Emond
, RK Lansigan
, GA Ballarino
, DD Carlson
, RJF Loos
, D Gilbert-Diamond
Brief Summary: This genetic epidemiology study genotyped n=248 unrelated children aged 9-12 years, computed 4 weighted polygenic risk scores (PRS), and investigated the associations between (1) appetitive traits and BMI, (2) PRSs and BMI, and (3) PRSs and appetitive traits. Appetite traits were evaluated using an obesogenic appetite score, which was calculated by combining mean scores of the food approach and food avoidance domains from the Child Eating Behavior Questionnaire....