ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

Page 1 of about 7 results

ey0017.9-2 | Fertility-Related Issues | ESPEYB17

9.2. Pregnancy, time to pregnancy and obstetric outcomes among female childhood cancer survivors: Results of the DCOG LATER-VEVO study

Dijk M Van , FE van Leeuwen , A Overbeek , CB Lambalk , MM van den Heuvel-Eibrink , W van Dorp , WJ Tissing , LC Kremer , JJ Loonen , B Versluys , D Bresters , CM Ronckers , HJ van der Pal , CCM Beerendonk , GJL Kaspers , E van Dulmen-den Broeder , MH van den Berg

To read the full abstract: J Cancer Res Clin Oncol. 2020 Jun;146(6):1451–1462. marloes.vandijk@amsterdamumc.nlChemo- and radiotherapy administered during childhood may compromise female reproductive function leading to premature depletion of the ovarian follicle pool. Childhood cancer survivors (CCS) women who pursue pregnancy may experience a lengthening of the time required to become pr...
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ey0016.9-8 | Fertility Issues in Chronic Diseases: New Insights | ESPEYB16

9.8. Long-term effects of childhood cancer treatment on hormonal and ultrasound markers of ovarian reserve

MH van den Berg , A Overbeek , CB Lambalk , GJL Kaspers , D Bresters , MM van den Heuvel-Eibrink , LC Kremer , JJ Loonen , HJ van der Pal , CM Ronckers , WJE Tissing , AB Versluys , M van der Heiden-van der Loo , AC Heijboer , M Hauptmann , JWR Twisk , JSE Laven , CCM Beerendonk , FE van Leeuwen , E van Dulmen-den Broeder , DCOG LATER-VEVO Study Group

Hum Reprod. 2018 Jul 6. [Epub ahead of print]. doi: 10.1093/humrep/dey229Childhood cancer treatment may compromise ovarian function in female childhood cancer survivors (CCSs), leading to delayed or arrested puberty, infertility, subfertility and adverse pregnancy outcomes. This Dutch nationwide retrospective cohort study collected measurements performed between 2008 and 2...
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ey0021.9-6 | Fertility Issues | ESPEYB21

9.6. Reproductive outcomes and reproductive health care utilization among male survivors of childhood cancer: a DCCSS-LATER study

JJM Claessens , A Penson , EM Bronkhorst , LCM Kremer , E van Broeder 7 , Heiden-van der Loo M van der , WJE Tissing , Pal HJH van der , NMA Blijlevens , Heuvel-Eibrink MM van den , AB Versluys , D Bresters , CM Ronckers , I Walraven , CCM Beerendonk , JJ Loonen , group. Dutch later study

Brief Summary: The nationwide Dutch Childhood Cancer Survivor (CCS) LATER cohort study assessed by questionnaire the reproductive outcomes and reproductive health care in 1317 male CCS and 407 male siblings. This included 491 CCS and 185 siblings who expressed a previous or current desire for children. Fewer CCS than siblings reported having biological children (65% vs. 88%). The type of conception was similar between CCSs and siblings (spontaneous conception in 90% of both gr...
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ey0020.7-8 | Bone Health in Childhood Cancer Survivors | ESPEYB20

7.8. Risk and determinants of low and very low bone mineral density and fractures in a national cohort of Dutch adult childhood cancer survivors (DCCSS-LATER): a cross-sectional study

JE van Atteveld , DTC de Winter , VG Pluimakers , M Fiocco , RAJ Nievelstein , MGG Hobbelink , ACH de Vries , JJ Loonen , E van Dulmen-den Broeder , HJ van der Pal , SMF Pluijm , LCM Kremer , CM Ronckers , M van der Heiden-van der Loo , AB Versluijs , M Louwerens , D Bresters , HM van Santen , DS Olsson , I Hoefer , SAA van den Berg , J den Hartogh , WJE Tissing , SJCMM Neggers , MM van den Heuvel-Eibrink , Dutch LATER study group

Brief summary: This Dutch cross-sectional study aimed to assess risk factors for impaired bone mineral density (BMD) and fractures (particularly vertebral fractures) in adult survivors of childhood cancer. The relationships between low BMD (Z-score ≤–1), very low BMD (Z-score ≤–2), fractures, vertebral fractures, and demographic, treatment-related, endocrine, and lifestyle-related factors was analyzed by logistic regression.<p class=...
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ey0020.7-15 | Long-Term Surveillance for Endocrine Complications in Childhood Cancer Survivors | ESPEYB20

7.15. Frailty and sarcopenia within the earliest national Dutch childhood cancer survivor cohort (DCCSS-LATER): a cross-sectional study

JE van Atteveld , DTC de Winter , VG Pluimakers , M Fiocco , RAJ Nievelstein , MGG Hobbelink , LCM Kremer , MA Grootenhuis , H Maurice-Stam , WJE Tissing , ACH de Vries , JJ Loonen , E van Dulmen-den Broeder , HJH van der Pal , SMF Pluijm , M van der Heiden-van der Loo , AB Versluijs , M Louwerens , D Bresters , HM van Santen , I Hoefer , SAA van den Berg , J den Hartogh , JHJ Hoeijmakers , SJCMM Neggers , MM van den Heuvel-Eibrink , Dutch LATER study group

Brief summary: This cross-sectional study explored the risk factors for pre-frailty, frailty, and sarcopenia in a cohort of Dutch childhood cancer survivors diagnosed between 1963 and 2001.Frailty was defined as the presence of at least two (pre-frailty) or three (frailty) of the following criteria: low appendicular lean mass (low percentage of lean tissue in the limbs assessed by dual-energy X-ray absorptiometry, DXA), low muscle strength (measured with...
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ey0018.9-8 | Genetic susceptibility to treatment-related gonadotoxicity | ESPEYB18

9.8. Possible modification of BRSK1 on the risk of alkylating chemotherapy-related reduced ovarian function

ALF van der Kooi , M van Dijk , L Broer , MH van den Berg , JSE Laven , FE van Leeuwen , CB Lambalk , A Overbeek , JJ Loonen , HJ van der Pal , WJ Tissing , B Versluys , D Bresters , CCM Beerendonk , CR Ronckers , M van der Heiden-van der Loo , GL Kaspers , ACH de Vries , LL Robison , MM Hudson , W Chemaitilly , J Byrne , C Berger , E Clemens , U Dirksen , J Falck Winther , SD Fossa , D Grabow , R Haupt , M Kaiser , T Kepak , J Kruseova , D Modan-Moses , SMF Pluijm , C Spix , O Zolk , P Kaatsch , JH Krijthe , LC Kremer , Y Yasui , RJ Brooke , AG Uitterlinden , M van den Heuvel-Eibrink , E Mvan Dulmen-den Broeder

Hum Reprod. 2021; 36: 1120–1133. https://pubmed.ncbi.nlm.nih.gov/33582778/This multi-centre retrospective cohort study identifies that common genetic variants in DNA repair genes modify the damage induced by alkylating agents on ovarian function, as assessed by low AMH levels.Alkylating agents are known to induce apoptosis of cancer cells by damaging DNA replicat...
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ey0019.9-14 | Fertility issues and reproductive outcomes in childhood cancer survivors | ESPEYB19

9.14. Effect of Genetic Variation in CYP450 on gonadal impairment in a European cohort of female childhood cancer survivors, based on a candidate gene approach: results from the PanCareLIFE study

der Perk MEM van , L Broer , Y Yasui , LL Robison , MM Hudson , JSE Laven , der Pal HJ van , WJE Tissing , B Versluys , D Bresters , GJL Kaspers , Vries ACH de , CB Lambalk , A Overbeek , JJ Loonen , CCM Beerendonk , J Byrne , C Berger , E Clemens , U Dirksen , Winther J Falck , SD Fossa , D Grabow , M Muraca , M Kaiser , T Kepak , J Kruseova , D Modan-Moses , C Spix , O Zolk , P Kaatsch , JH Krijthe , LCM Kremer , RJ Brooke , JL Baedke , RHN van Schaik , JN van den Anker , AG Uitterlinden , AME Bos , FE van Leeuwen , E van Dulmen-den Broeder , ALF van der Kooi , MM van den Heuvel-Eibrink

On Behalf Of The PanCareLIFE Consortium. m.e.m.vanderperk@prinsesmaximacentrum.nl Cancers (Basel). 2021; 13: 4598. PMID: 34572825.Brief Summary: This cohort study of female childhood cancer survivors (CCS) identified associations between specific nucleotide polymorphisms (SNP) in cytochrome P450 (CYP450) enzymes, which metabolize alkylating agents (AA), and variability in AA-induced o...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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