ISSN 1662-4009 (online)

ey0021.6-15 | Cardiovascular Outcomes in Transgender People | ESPEYB21

6.15. Cardiovascular disease in transgender people: a systematic review and meta-analysis

LM van Zijverden , CM Wiepjes , JJK van Diemen , A Thijs , M den Heijer

Brief Summary: This systematic review and meta-analysis included 22 studies, with a total of 19,893 transgender women, 14,840 transgender men, 371,547 cisgender men, and 434,700 cisgender women, to assess the occurrence of cardiovascular events. The risk of the combined outcome (stroke, myocardial infarction or thrombosis) was 40% higher in transgender people compared to cisgender people of the same birth-registered sex.Gender-affirming therapy may play ...