ey0019.14-5 | Steroidogenesis and beyond | ESPEYB19
VK Yadav
, JM Berger
, P Singh
, P Nagarajan
, G Karsenty
J Clin Invest 2022;132(4):e153752 doi: 10.1172/JCI153752Brief summary: Using rodent and primate models, this study shows a classical endocrine feedback loop, where bone-derived osteocalcin enhances adrenal steroidogenesis, and the inactivation of osteocalcin signalling impairs adrenal growth and steroidogenesis.This study provides important evidence on the existence of the bo...