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15.6 Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist

HS Taylor , LC Giudice , BA Lessey , MS Abrao , J Kotarski , DF Archer , MP Diamond , E Surrey , NP Johnson , NB Watts , JC Gallagher , JA Simon , BR Carr , WP Dmowski , N Leyland , JP Rowan , WR Duan , J Ng , B Schwefel , JW Thomas , RI Jain , K Chwalisz

To read the full abstract: N Engl J Med 2017;377:28-40We highlight this paper for 3 reasons. First, remarkably there are few robust data on effective treatment options for endometriosis. Subcutaneous GnRH antagonists are sometimes used off-label, but with very limited evidence. Secondly, the clear findings here confirm the pathogenesis of endometriosis as being driven by an over-act...

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ESPE Yearbook of Paediatric Endocrinology

15.6 Treatment of Endometriosis-Associated Pain with Elagolix, an Oral GnRH Antagonist

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