ISSN 1662-4009 (online)

ey0021.8-7 | Important for Clinical Practice | ESPEYB21

8.7. Parental concerns about genital differences in children with congenital adrenal hyperplasia persist regardless of the selected intervention

J Alderson , M Thornton , M Skae , J Jones , N Nicoll , D Harcourt , M Woodward , EC Crowne

Brief Summary: This qualitative study investigated parental communication with their daughters regarding variation in clitoral size related to severity of classical congenital adrenal hyprplasia (CAH). The authors conducted semi-structured in-person interviews with 24 parents of children with a specific genital difference, without direct exploration of parental values regarding the clitoris or the application of adequate psychosocial care.Comment: CAH du...

ey0015.15-3 | Interventions for overweight and obesity do work | ESPEYB15

15.3 Diet, physical activity and behavioural interventions for the treatment of overweight or obese children from the age of 6 to 11 years

E Mead , T Brown , K Rees , LB Azevedo , V Whittaker , D Jones , J Olajide , GM Mainardi , E Corpeleijn , C O'Malley , E Beardsmore , L Al-Khudairy , L Baur , MI Metzendorf , A Demaio , LJ Ells

To read the full abstract: Cochrane Database Syst Rev 2017;6:CD012651Here, the authors report an update of a Cochrane review, which was first published in 2003, and last updated in 2009. However, given the complexity of the evidence, the current update is now split into 6 reviews addressing diff...

ey0017.8-17 | Food for Thought | ESPEYB17

8.17. Plasma renin measurements are unrelated to mineralocorticoid replacement dose in patients with primary adrenal insufficiency

R Pofi , A Prete , V Thornton-Jones , J Bryce , SR Ali , Ahmed S Faisal , A Balsamo , F Baronio , A Cannuccia , A Guven , T Guran , F Darendeliler , C Higham , W Bonfig , L de Vries , TASS Bachega , MC Miranda , BB Mendonca , V Iotova , M Korbonits , NP Krone , R Krone , A Lenzi , W Arlt , RJ Ross , AM Isidori , JW Tomlinson

To read the full abstract: J Clin Endocrinol Metab. 2020; 105(1): dgz055. PMID: 31613957.Mineralocorticoid (MC) replacement therapy along with glucocorticoid (GC) replacement is crucial to avoid life-threating adrenal crises in Addison´s disease (AD) and in classical CAH (1–3). MC is administered with the aim of achieving plasma renin concentration (PRC) within the upper limit of ...