ISSN 1662-4009 (online)

ey0018.11-15 | New insight into preconceptional and prenatal programming | ESPEYB18

11.15. Sex-specific programming effects of parental obesity in pre-implantation embryonic development

K Hedegger , J Philippou-Massier , S Krebs , H Blum , S Kunzelmann , K Forstemann , M Gimpfl , AA Roscher , R Ensenauer , E Wolf , M Dahlhoff

Int J Obes (Lond). 2020 May;44(5):1185–1190. https://pubmed.ncbi.nlm.nih.gov/31776435/These authors investigated the effect of maternal and paternal obesity on gene expression level in the mouse blastocyst. Firstly, they show that female and male offspring were differentially sensitive to an obesogenic maternal environment in the early phase of preimplantation. Male blastocysts from o...