ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0021.9-5 | Fertility Issues | ESPEYB21

9.5. Fertility potential and gonadal function in survivors of reduced-intensity hematopoietic stem cell transplantation

SJ Rotz , BK Hamilton , W Wei , I Ahmed , SA Winston , S Ballard , RJ Bernard , P Carpenter , N Farhadfar , C Ferraro , BD Friend , NJ Gloude , RJ Hayashi , K Hoyle , K Jenssen , J Koo , CJ Lee , L Mariano , R Nawabit , A Ngwube , N Lalefar , R Phelan , L Perkins , A Rao , A Rayes , T Sandheinrich , L Stafford , K Tomlinson , S Whiteside , C Wiedl , K Myers

Brief Summary: This multicenter, international, retrospective study evaluated fertility potential and gonadal function in 326 adolescent and young adult cancer survivors. Risk factors for impairment included hematopoietic stem cell transplantation (HCT) conditioning regimen (myeloablative conditioning, MAC vs reduced-intensity conditioning, RIC).The prevalence of gonadal hormone failure in females was 55.3% (defined as FSH >30 mIU/mL with an estradio...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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