ey0015.15-13 | The importance of being earnest about diurnal variation | ESPEYB15
Z Bahrami-Nejad
, ML Zhao
, S Tholen
, D Hunerdosse
, KE Tkach
, S van Schie
, M Chung
, MN Teruel
To read the full abstract: Cell Metabolism 2018;27:854-868. e8People gain weight due to treatment with glucocorticoid (GC) drugs, but also in chronic stress and disrupted circadian rhythms. We now learn that fat-cell maturation increases if the trough in exposure to GC lasts less than 12 hours. A long pulse of glucocorticoids lasting 48 hours led most of the cells to differentiate under the ...