ISSN 1662-4009 (online)

ey0018.5-10 | Translational highlights | ESPEYB18

5.10. Single cell transcriptomic analysis of human pluripotent stem cell chondrogenesis

Wu Chia-Lung , Dicks Amanda , Steward Nancy , Tang Ruhang , Katz Dakota B , Choi Yun-Rak , Guilak Farshid

Nat Commun. 2021 Jan 13;12(1):362 Abstract: https://pubmed.ncbi.nlm.nih.gov/33441552/In brief: Heterogenous differentiation patterns and low yields limit the use of human induced pluripotent stem cells (hiPSCs) for the generation of cartilage. In the present work, bulk- and single cell RNA sequencing during chondrogenic differentiation were used to identify regulatory networks resp...