ISSN 1662-4009 (online)

ey0021.4-5 | Important for Clinical Practice | ESPEYB21

4.5. Cerebrovascular abnormalities in adults born SGA at 12 years after growth hormone cessation compared to controls

DJ Dorrepaal , WJ Goedegebuure , L Smagge , M van der Steen , A van der Lugt , ACS Hokken-Koelega

Brief Summary: This single-center, prospective study used brain MRI to assess the prevalence of cerebrovascular abnormalities in a large cohort of adult patients born SGA and treated with GH during childhood, 12 years after rhGH treatment cessation. GH treatment was not associated with a higher incidence of aneurysms, intracerebral hemorrhages, microbleeds or other vascular abnormalities.The French population-based cohort of the Safety and Appropriatenes...