ESPE Yearbook of Paediatric Endocrinology

Brief Summary: This pilot study assessed the feasibility and impact of continuous glucose monitoring (CGM) in 9 adolescents with T2D. CGM use lowered HbA1c by up to 3.8% in participants who consistently used the device.Comment: Large cohort studies investigating complications in children and adolescents with T2D have clearly shown a higher incidence of complications compared to both adults with T2D and children with type 1 diabetes (T1D). These complicat...

Brief summary: This randomized, double-blind, phase 3 trial of youths with inadequately controlled T2D, dulaglutide treatment was superior to placebo in reducing the glycated hemoglobin level at 26 weeks.Comment: T2D in children and adolescents is an aggressive disease with early onset of complications, leading to significant morbidity and mortality. After three decades with no efficient treatment, there is finally light at the end of the tunnel.<p c...

Brief summary: A significant increase in the incidence T2D occurred in the USA during the COVID-19 pandemic, particularly among children with obesity and males.Comment: This is the first multicenter report on the incidence of T2D during the first year of the COVID-19 pandemic in the USA. The average number of new diagnoses per year in the two pre-pandemic years was 825, compared with 1463 during the first pandemic year. This increase of 77% is significan...