ESPE Yearbook of Paediatric Endocrinology

Brief Summary: This cross-sectional study explored the relationship between obesity and skeletal muscle protein synthesis, focusing on the expression of IGF-I and its mRNA splice variants. It provides insights into how obesity might impair protein synthesis and IGF-I levels, potentially contributing to the reduced muscle quality observed in obese patients.This study explored IGF-I expression in the muscles of obese patients as a potential factor contribu...