ISSN 1662-4009 (online)

ey0021.10-17 | New Hopes | ESPEYB21

10.17. Non-invasive quantification of stem cell-derived islet graft size and composition

V Lithovius , S Lahdenpohja , H Ibrahim , J Saarimaki-Vire , L Uusitalo , H Montaser , al. et

Brief Summary: This experimental study used positron emission tomography (PET) as non-invasive method to monitor stem cells-islet grafts. [18F]exendin and [18F]FDOPA PET showed potential as non-invasive methods to assess stem cells-islet graft size and aspects of graft composition.Stem cell-derived islets (SC-islets) are used as an emerging cell replacement therapy for insulin-dependent diabetes (1). Non-invasive long-term monitorin...