ISSN 1662-4009 (online)

ey0019.11-4 | New findings in adipose tissue biology | ESPEYB19

11.4. Expression of the adipocyte progenitor markers MSCA1 and CD36 is associated with adipose tissue function in children

M Hanschkow , N Boulet , E Kempf , A Bouloumie , W Kiess , R Stein , A Korner , K Landgraf

kathrin.landgraf@medizin.uni-leipzig.de JCEM 2022; 107(2): e836–e851https://pubmed.ncbi.nlm.nih.gov/34448000Brief Summary: This study investigated the association of the novel adipose-derived stem cell (ASC) markers Mesenchymal Stem cell Antigen 1 (MSCA1) and CD36 with adipose tissue function in samples collected from children...

ey0018.12-11 | Metabolic Syndrome | ESPEYB18

12.11. The effect of green Mediterranean diet on cardiometabolic risk; a randomised controlled trial

G Tsaban , A Yaskolka Meir , E Rinott , H Zelicha , A Kaplan , A Shalev , A Katz , A Rudich , A Tirosh , I Shelef , I Youngster , S Lebovitz , N Israeli , M Shabat , D Brikner , E Pupkin , M Stumvoll , J Thiery , U Ceglarek , JT Heiker , A Korner , K Landgraf , M von Bergen , M Bluher , MJ Stampfer , I Shai

Heart. 2020 Nov 23:heartjnl-2020-317802. doi: 10.1136/heartjnl-2020-317802. PMID: 33234670.In brief: This parallel-arm trial randomly assigned 294 adults with abdominal obesity/dyslipidemia to 1 of 3 dietary guidelines: healthy diet; Mediterranean diet; or ‘green Mediterranean’ diet. All groups received physical activity guidelines. Weight loss was higher in the two...

ey0021.14-7 | Epi-/Genetics | ESPEYB21

14.7. Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs

Tomar A. , Gomez-Velazquez M. , Gerlini R. , Comas-Armangue G. , Makharadze L. , Kolbe T. , Boersma A. , Dahlhoff M. , Burgstaller J.P. , Lassi M. , Darr J. , Toppari J. , Virtanen H. , Kuhnapfel A. , Scholz M. , Landgraf K. , Kiess W. , Vogel M. , Gailus-Durner V. , Fuchs H. , Marschall S. , de Angelis M. Hrabě , Kotaja N. , Korner A. , Teperino R.

Brief Summary:This study in mice and humans shows how paternal overweight at conception affects the metabolism of their offspring. Sperm-borne mt-sncRNAs (mitochondrial encoded or derived small non-coding RNAs) are altered by a 2-week high fat diet (HFD) challenge in mice, likely through specific upregulation of mt-tsRNAs (mitochondrial transfer RNAs) caused by mitochondrial dysfunction. In humans, mt-tsRNAs in spermatozoa correlate with body mass index. Genetically engineered...