ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0021.8-5 | Important for Clinical Practice | ESPEYB21

8.5. High-resolution daily profiles of tissue adrenal steroids by portable automated collection

TJ Upton , E Zavala , P Methlie , O Kampe , S Tsagarakis , M Oksnes , S Bensing , DA Vassiliadi , MA Grytaas , IR Botusan , G Ueland , K Berinder , K Simunkova , M Balomenaki , D Margaritopoulos , N Henne , R Crossley , G Russell , ES Husebye , SL Lightman

Brief Summary: This paper describes a novel ambulatory fraction collector that can be used with microdialysis to obtain high resolution steroid profiles over a 24-hour period.Comment: The natural circadian and ultradian secretion of adrenal hormones makes single timepoint measurements of these hormones uninformative for clinical decision making (1-3). Repeated sampling during the day requires admission into an atypical, and often disruptive, clinical set...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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