ISSN 1662-4009 (online)

ey0015.12-10 | New Hormones | ESPEYB15

12.10 The Association Between Serum Vaspin and Omentin-1 Levels in Obese Children with Metabolic Syndrome

M Buyukinan , M Atar , U Can , O Pirgon , A Guzelant , I Deniz

To read the full abstract: J Obes 2018;16:76-81In this study, a lower level of serum omentin-1 and a higher level of vaspin were detected in pubertal obese children with MetS compared with obese children without MetS. MetS is characterized by central obesity, and increased visceral adipose tissue mass is associated with higher prevalence of insulin resistance; these pose risks for T2DM and cardio...

ey0021.13-9 | Endocrinology | ESPEYB21

13.9. 17α Hydroxylase/17,20 lyase deficiency: clinical features and genetic insights from a large Turkey cohort

Z Siklar , E Camtosun , S Bolu , M Yildiz , A Akinci , F Bas , İ Dundar , A Bestas , E Unal , P Kocaay , T Guran , G Buyukyilmaz , AK Ugurlu , BG Tosun , I Turan , E Kurnaz , B Yuksel , D Turkkahraman , A Cayir , G Celmeli , EN Gonc , BS Eklioğlu , S Cetinkaya , SK Yilmaz , ME Atabek , M Buyukinan , E Arslan , E Mengen , EDP Cakir , M Karaoglan , N Hatipoglu , Z Orbak , A Ucar , N Akyurek , ED Akbas , E Isik , SB Kaygusuz , ZK Sutcu , G Seymen , M Berberoglu

Brief Summary: This retrospective cohort study analyzed data from 97 cases of 17α hydroxylase/17,20 lyase deficiency identified in Turkey. It focused on diagnostic testing, laboratory characteristics, long-term outcomes and therapeutic management.This nationwide study focuses on 17α-Hydroxylase/17,20-Lyase deficiency (17OHD), a rare form of congenital adrenal hyperplasia (CAH) caused by mutations in the CYP17A1 gene. The research aims to evalua...