ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0018.2-7 | Neonatal hypoglycaemia | ESPEYB18

2.7. Possible new strategies for the treatment of congenital hyperinsulinism

J Sikimic , T Hoffmeister , A Gresch , J Kaiser , W Barthlen , C Wolke , I Wieland , U Lendeckel , P Krippeit-Drews , M Dufer , G Drews

Front Endocrinol (Lausanne). 2020 Oct 27;11:545638. doi: 10.3389/fendo.2020.545638. PMID: 33193079.Using human islets from CHI patients and islets from ABCC8 (SUR1) knockout mice, the authors tested several novel compounds to inhibit insulin over-secretion. These novel compounds targeted KATP channels as well as KATP indepe...
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Published by BioScientifica

ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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