Abstract Search

10.10. ‘I’m essentially his pancreas’: Parent perceptions of diabetes burden and opportunities to reduce burden in the care of children <8 years old with type 1 diabetes

PV Commissariat , KR Harrington , AL Whitehouse , KM Miller , ME Hilliard , M Van Name , DJ DeSalvo , WV Tamborlane , BJ Anderson , LA DiMeglio , LM Laffel

To read the full abstract: Pediatr Diabetes. 2020 Mar;21(2):377383. doi: 10.1111/pedi.12956. PMID: 31808586Across all age groups, management of type 1 diabetes (T1DM) places substantial workload, responsibility and emotional burden, such as worries and stress, on families. This study explored parent perceptions of the burdens of caring for very young children with T1DM. Semi-structured qu...

0 shares

ey0020.10-7 | New Drugs for Children with T2DM | ESPEYB20

10.7. Maternal diabetes in youth-onset type 2 diabetes is associated with progressive dysglycemia and risk of complications

RD Shah , SD Chernausek , L El Ghormli , ME Geffner , J Keady , MM Kelsey , R Farrell , B Tesfaldet , JB Tryggestad , M Van Name , E Isganaitis

Brief summary: This analysis of data from the TODAY study examined the impact of parental diabetes on outcomes in young individuals with T2D during over 12 years of follow-up. This novel observation demonstrates that parental diabetes affects not only earlier T2D onset, but also more rapid long-term progression and more complications.Comment: This study showed that T2D diagnosis in either parent was associated with younger age at T2D diagnosis in their c...

0 shares

ey0020.8-1 | Clinical Trials – New Treatments | ESPEYB20

8.1. Effect of Verapamil on pancreatic beta cell function in newly diagnosed pediatric type 1 diabetes: A randomized clinical trial

GP Forlenza , J McVean , RW Beck , C Bauza , R Bailey , B Buckingham , LA DiMeglio , JL Sherr , M Clements , A Neyman , C Evans-Molina , EK Sims , LH Messer , L Ekhlaspour , R McDonough , M Van Name , D Rojas , S Beasley , S DuBose , C Kollman , A Moran , CLVer Study Group

Brief summary: In this double-blind, randomized clinical trial conducted in 6 US centres, 88 children and adolescents (aged 717 years) with newly diagnosed type 1 diabetes (T1D) were randomized to either once-daily oral verapamil or placebo, within 1 month from diagnosis. Treatment with verapamil led to better stimulated C-peptide secretion at 52 weeks post-diagnosis, with levels 30% higher compared to placebo.Verapamil is a calcium channel blocker...

0 shares

ESPE Yearbook of Paediatric Endocrinology

10.10. ‘I’m essentially his pancreas’: Parent perceptions of diabetes burden and opportunities to reduce burden in the care of children <8 years old with type 1 diabetes

10.7. Maternal diabetes in youth-onset type 2 diabetes is associated with progressive dysglycemia and risk of complications

8.1. Effect of Verapamil on pancreatic beta cell function in newly diagnosed pediatric type 1 diabetes: A randomized clinical trial

BiosciAbstracts