ESPE Yearbook of Paediatric Endocrinology

Brief Summary: This narrative review summarized 75 published studies on reproductive function in survivors of childhood, adolescent, and young adult Hodgkin lymphoma (HL). 41 papers reported on 5057 female HL survivors. Most young female survivors had regular menstrual cycles. The incidence of premature ovarian failure (POI) varied between 6-34%. Biochemical evidence for impaired ovarian reserve or function was frequent (low AMH 55–59%. elevated FSH 17–100%). 51 stud...