ESPE Yearbook of Paediatric Endocrinology

Brief summary: This cross-sectional single tertiary center study analyzed the aspects of sexual life and fertility desire among a large cohort of adults with 46,XY DSD in Brazil. The influence of critical variables such as external genital appearances, prenatal androgen exposure, and gender change in the sexuality of 46,XY DSD people were investigated.There is sparse literature on the sexual function of 46,XY DSD conditions due to their rarity and hetero...

Brief summary: This translational study showed an increased plasma expression of miR-210 in individuals with 46,XY DSD compared to the control population and also showed a positive association between the presence of atypical genitalia and plasma levels of miR-210 expression in individuals with 46,XY DSD. The findings of this study contribute to a novel perspective on the possible role of miRNAs in the development of the male external genitalia and in the development of phenot...