ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: J Public Health (Oxf) 2017:1-9Our efforts to control overweight and obesity in children are severely hampered because most of their parents (and indeed most of their health professionals!) cannot visually recognise an obese child, let alone one who is overweight. This is particularly difficult at around the ages 4-6 years old because this coincides with the BMI n...

To read the full abstract: N Engl J Med 2017;377:13-27Other estimates of the global trends and projections in obesity have been published. In this regard, the current analysis provides similar, albeit equally worrying, data on the trends towards more obesity across all regions of the world. Moreover, a particular advance of this current study, which was funded by the Bill and Melind...

Brief Summary: This cross-sectional analysis showed that DNA methylation (DNAm) patterns differ between youth-onset and adult-onset T2D. In utero exposure to maternal diabetes was linked to these distinct changes. These findings highlight unique molecular pathways disrupted by youth-onset T2D, and suggest potential intervention targets to prevent its health impacts.Comment: Growing evidence suggests that T2D in children and adolescents is essentially dif...