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13.10. Race-dependent association of high-density lipoprotein cholesterol levels with incident coronary artery disease

NA Zakai , J Minnier , MM Safford , I Koh , MR Irvin , S Fazio , M Cushman , VJ Howard , N Pamir

In Brief: In this US cohort study of 30,239 Black and White individuals aged >=45 years followed up for a median of 10 years, low baseline levels of HDL-Cholesterol (HDL-C) were associated with increased risk of coronary heart disease (CHD) in White (HR: 1.22; 95% CI: 1.051.43) but not in Black (HR: 0.94; 95% CI: 0.781.14) adults (P-interaction by race =0.08).Comment: The established clinical risk factors for coronary heart disea...

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ey0015.10-20 | Prevention | ESPEYB15

10.20 Effect of hydrolyzed infant formula vs conventional formula on risk of T1DM. The TRIGR randomized clinical trial

Writing Group for the TRIGR Study Group , M Knip , HK Åkerblom , E Al Taji , D Becker , J Bruining , L Castano , T Danne , C de Beaufort , HM Dosch , J Dupre , WD Fraser , N Howard , J Ilonen , D Konrad , O Kordonouri , JP Krischer , ML Lawson , J Ludvigsson , L Madacsy , JL Mahon , A Ormisson , JP Palmer , P Pozzilli , E Savilahti , M Serrano-Rios , M Songini , S Taback , Vaarala , NH White , SM Virtanen , R Wasikowa

To read the full abstract: JAMA. 2018;319:38-48Earlier observational studies showed that dietary exposure to complex proteins in newborns and early infants is associated with beta cell autoimmunity and increase the risk for T1DM. Several studies avoiding certain proteins, such as gluten and casein, have been conducted without reducing the risk for T1D in genetically susceptible children. Theref...

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ESPE Yearbook of Paediatric Endocrinology

13.10. Race-dependent association of high-density lipoprotein cholesterol levels with incident coronary artery disease

10.20 Effect of hydrolyzed infant formula vs conventional formula on risk of T1DM. The TRIGR randomized clinical trial

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