ISSN 1662-4009 (online)

ey0021.9-14 | Growth Problems in Cancer Survivors | ESPEYB21

9.14. Exploring height outcomes with adjuvant aromatase inhibition in growth hormone-deficient male survivors of childhood cancer

NI Pollock , M Song , AJ Wolf , Y Li , CP Hawkes , N Motamedi , MR Denburg , S Mostoufi-Moab

Brief Summary: This single-center, retrospective cohort study compared the final adult height (FAH) of 92 male childhood cancer survivors (CCS) with growth hormone deficiency GHD) treated with growth hormone alone (monotherapy) or in combination with an aromatase inhibitor. The addition of AI to GH therapy did not improve FAH.This study from the Children’s Hospital of Philadelphia is the most extensive study on the role of AI associated with GH in i...