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ey0018.8-3 | Important for Clinical Practice | ESPEYB18

8.3. Modified-release hydrocortisone in congenital adrenal hyperplasia

DP Merke , A Mallappa , W Arlt , A Brac de la Perriere , A Linden Hirschberg , A Juul , J Newell-Price , CG Perry , A Prete , DA Rees , N Reisch , N Stikkelbroeck , P Touraine , K Maltby , FP Treasure , J Porter , RJ Ross

J Clin Endocrinol Metab 2021; 106(5): e2063e2077.https://pubmed.ncbi.nlm.nih.gov/33527139/The authors report the findings of a 6-month, randomized, phase 3 trial, with a single arm extension, to investigate the efficacy, safety and tolerability of modified release hydrocortisone (MC-HC) replacement therapy versus standard glucocorticoid replacement therapy in 122 adult patients with c...

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ey0016.8-9 | Clinical Trials - New Treatments | ESPEYB16

8.9. A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest

GD Perkins , C Ji , CD Deakin , T Quinn , JP Nolan , C Scomparin , S Regan , J Long , A Slowther , H Pocock , JJM Black , F Moore , RT Fothergill , N Rees , L O'Shea , M Docherty , I Gunson , K Han , K Charlton , J Finn , S Petrou , N Stallard , S Gates , R Lall , Collaborators PARAMEDIC2

To read the full abstract: N Engl J Med. 2018; 379(8): 711721.In attempting to reduce the rate of death and disability associated with cardiac arrest worldwide, emergency medical workers have few effective treatments other than early initiation of cardiopulmonary resuscitation (CPR) and prompt defibrillation. Epinephrine (adrenaline) has potentially beneficial effects in cardiac ar...

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ESPE Yearbook of Paediatric Endocrinology

8.3. Modified-release hydrocortisone in congenital adrenal hyperplasia

8.9. A Randomized Trial of Epinephrine in Out-of-Hospital Cardiac Arrest

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