ey0020.1-5 | Follow-up Paper from the 2022 Yearbook | ESPEYB20
JN Gallant
, SC Chen
, CA Ortega
, SL Rohde
, RH Belcher
, JL Netterville
, N Baregamian
, H Wang
, J Liang
, F Ye
, YE Nikiforov
, MN Nikiforova
, VL Weiss
Brief summary: In 2021 and 2022, two important publications on pediatric thyroid carcinomas revealed a distinct molecular landscape compared to adult thyroid carcinomas (1,2). Pediatric differentiated thyroid carcinoma was mainly caused by fusion oncogenes, especially in children younger than 10 years (93%), compared to children aged 1015 years (28%) and 1520 years old patients (14%). In contrast, PTC due to BRAF mutations showed increasing frequency with age (7%, ...