ESPE Yearbook of Paediatric Endocrinology

To read the full abstract: Diabetes Care 2020;43(1):187–95. doi: 10.2337/dc19-0708Short summary: Over 5 years follow-up, bariatric surgery compared with medical treatment resulted in dramatic attenuation of diabetic kidney disease (DKD) in adolescents with T2DM and severe obesity, beyond the impact of improved glycaemic control and weight loss.Comment</em...

The New England Journal of Medicine 2021;385(5):416-26. doi: 10.1056/NEJMoa2100165Brief Summary: This multicenter observational study assessed the cumulative incidence of diabetic complications in 500 adolescents with Type 2 diabetes (T2DM), followed from 2011 to 2020. After only 13 years from T2DM diagnosis, higher complication rates were observed than those reported for pediatric patients wit...

Brief Summary: The authors performed exploratory analyses to identify distinct eGFR trajectories associated with risk of albuminuria in 377 adolescents with T2D. The findings underscore the importance of annual GFR assessments in young people with T2D.Comment: Diabetic kidney disease (DKD) is the primary microvascular complication in adolescents with T2D, and is a leading cause of morbidity and mortality. Albuminuria is the earliest clinical indicator of...