ey0021.11-15 | Adipocyte Dysfunction and Obesity Related Comorbidities | ESPEYB21
F Klingelhuber
, S Frendo-Cumbo
, M Omar-Hmeadi
, L Massier
, P Kakimoto
, AJ Taylor
, M Couchet
, S Ribicic
, M Wabitsch
, AC Messias
, A Iuso
, TD Muller
, M Ryden
, N Mejhert
, N Krahmer
Brief Summary: This study created a temporally- and spatially-resolved proteomic atlas of human adipogenesis. It highlights cell restructuring and spatial reorganization of metabolic pathways to optimize cells for lipid accumulation and identifies C19orf12 as a differentiation-induced protein that regulates lipid storage in adipocytes.This study provides a comprehensive and detailed proteomic map that captures the dynamic changes in protein abundance and...