Abstract Search

ey0018.11-14 | New insight into preconceptional and prenatal programming | ESPEYB18

11.14. Lifestyle intervention in pregnant women with obesity impacts cord blood DNA methylation, which associates with body composition in the offspring

J Jonsson , KM Renault , S Garcia-Calzon , A Perfilyev , AC Estampador , K Norgaard , M Vendelbo Lind , A Vaag , L Hjort , KF Michaelsen , E Malchau Carlsen , PW Franks , C Ling

Diabetes 2021 Apr;70(4):854–866. https://pubmed.ncbi.nlm.nih.gov/33431374/These authors performed a randomized trial of obese pregnant women (n=425) to investigate the effects of a pregnancy lifestyle intervention on epigenetic variations in umbilical cord blood, on neonatal body composition (DXA) and on offspring BMI in later life (up to 3 years). Offspring of mothers who re...

0 shares

ey0019.15-2 | Obesity | ESPEYB19

15.2. Postprandial glycaemic dips predict appetite and energy intake in healthy individuals

P Wyatt , SE Berry , G Finlayson , R O'Driscoll , G Hadjigeorgiou , DA Drew , HA Khatib , LH Nguyen , I Linenberg , AT Chan , TD Spector , PW Franks , J Wolf , J Blundell , AM Valdes

Nat Metab. 2021;3(4):523-9. doi: 10.1038/s42255-021-00383-x.PubMed ID: 33846643Brief summary: this study of around 1000 adults administered standard breakfast meals and showed wide variability and continuously monitored glucose levels up to 3 h afterwards. Notably, those individuals with lower glucose levels at 2 to 3 h after meals reported higher levels of appetite and consumed hundreds m...

0 shares

ey0019.15-4 | Diabetes | ESPEYB19

15.4. Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

A Wesolowska-Andersen , CA Brorsson , R Bizzotto , A Mari , A Tura , R Koivula , A Mahajan , A Vinuela , JF Tajes , S Sharma , M Haid , C Prehn , A Artati , MG Hong , PB Musholt , A Kurbasic , F De Masi , K Tsirigos , HK Pedersen , V Gudmundsdottir , CE Thomas , K Banasik , C Jennison , A Jones , G Kennedy , J Bell , L Thomas , G Frost , H Thomsen , K Allin , TH Hansen , H Vestergaard , T Hansen , F Rutters , P Elders , L t'Hart , A Bonnefond , M Canouil , S Brage , T Kokkola , A Heggie , D McEvoy , A Hattersley , T McDonald , H Teare , M Ridderstrale , M Walker , I Forgie , GN Giordano , P Froguel , I Pavo , H Ruetten , O Pedersen , E Dermitzakis , PW Franks , JM Schwenk , J Adamski , E Pearson , MI McCarthy , S Brunak , Consortium ID

Cell Rep Med. 2022;3(1):100477. doi: 10.1016/j.xcrm.2021.100477. PubMed ID: 35106505Brief summary: To explore clinical heterogeneity, this study analyzed baseline visit data on 726 adults with newly diagnosed Type 2 diabetes (T2D) adults and identified in 4 distinct profiles (clusters of phenotypes), which predicted differences in subsequent disease progression and anti-diabetic treatments...

0 shares

ESPE Yearbook of Paediatric Endocrinology

11.14. Lifestyle intervention in pregnant women with obesity impacts cord blood DNA methylation, which associates with body composition in the offspring

15.2. Postprandial glycaemic dips predict appetite and energy intake in healthy individuals

15.4. Four groups of type 2 diabetes contribute to the etiological and clinical heterogeneity in newly diagnosed individuals: An IMI DIRECT study

BiosciAbstracts