ESPE Yearbook of Paediatric Endocrinology

J Clin Endocrinol Metab. 2022; dgac271. PMID: 35512387 https://pubmed.ncbi.nlm.nih.gov/35512387/Brief Summary: This study, in a series of independent patient cohorts, developed and validated a clinical score, based on the circulating concentrations of 13 major steroid hormones, to detect and subtype Congenital Adrenal Hyperplasia (CAH).Steroidogenesis is a complex proc...

To read the full abstract: Nat Genet. 2018 Mar;50(3):432-442Maternal obesity is associated with poor outcomes across the reproductive spectrum including infertility, increased time to pregnancy, early pregnancy loss, congenital abnormalities and neonatal complications. Adverse effects are detectable as early as the oocyte and preimplantation embryo stage, and that these early effects may cont...

Brief Summary: These authors developed a fully autonomous robotic ultrasound (US) system for thyroid scanning (FARUS). The system consists of a six-degree-of-freedom UR3 manipulator that carries a linear US probe, a US probe fixture, a six-axis force/torque sensor and a Kinect camera. Using reinforcement learning, Bayesian optimization, and deep learning, the system dynamically adjusts the probe position and performs real-time segmentation of thyroid tissue and potential nodul...