ISSN 1662-4009 (online)

ey0019.7-13 | Basic Science | ESPEYB19

7.13. Multi- and transgenerational outcomes of an exposure to a mixture of endocrine-disrupting chemicals (EDCs) on puberty and maternal behavior in the female rat

D Lopez-Rodriguez , CF Aylwin , V Delli , E Sevrin , M Campanile , M Martin , D Franssen , A Gerard , S Blacher , E Tirelli , A Noel , A Lomniczi , AS Parent

Environ Health Perspect.2021 Aug;129(8):87003. doi: 10.1289/EHP8795. Epub 2021 Aug 12. PMID: 34383603. https://ehp.niehs.nih.gov/doi/10.1289/EHP8795?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmedBrief Summary: Using a rode...

ey0015.12-8 | New Mechanism (1) | ESPEYB15

12.8 Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection

CA Thaiss , M Levy , I Grosheva , D Zheng , E Soffer , E Blacher , S Braverman , AC Tengeler , O Barak , M Elazar , R Ben-Zeev , D Lehavi-Regev , MN Katz , M Pevsner-Fischer , A Gertler , Z Halpern , A Harmelin , S Aamar , P Serradas , A Grosfeld , H Shapiro , B Geiger , E Elinav

To read the full abstract: Science 2018;359:1376-1383The metabolic syndrome (MetS) is associated with dysfunctions of the intestinal barrier, leading to increased permeability and translocation of microbial molecules into the intestinal lamina propria and to circulation. The entry of pathogens through an impaired barrier leads to an increased risk of infection, as well as to chronic inflammation...