ey0020.7-2 | Gonadal Function and Fertility Issues in Childhood Cancer Survivors | ESPEYB20
G Rodari
, S Federici
, T Todisco
, G Ubertini
, A Cattoni
, M Pagano
, F Giacchetti
, E Profka
, V Citterio
, D Messetti
, V Collini
, D Soranna
, E Carbone
, M Arosio
, G Mantovani
, L Persani
, M Cappa
, M Bonomi
, C Giavoli
Brief summary: This longitudinal observational multicentre retrospective study, collected data on 95 young prepubertal or early pubertal girls (age >10.9 years, Tanner stage ≤2) with premature ovarian failure (POI) or hypogonadotropic hypogonadism (HH). Their hypogonadism was due to different causes and was treated with transdermal 17β-oestradiol, with a follow-up of at least 1 year. The study aimed to identify the most physiological and effective therapeutic sc...