ESPE Yearbook of Paediatric Endocrinology

grahamo@diabetesnsw.com.au Diabetes Res Clin Pract 2022, 183:109083. doi: 10.1016/j.diabres.2021.109083Brief Summary: The incidence of Type 1 diabetes (T1D) in children and adolescents is increasing in many nations. The 10th edition of the International Diabetes Federation Atlas reports that an estimated 108,300 youth aged < 15 years a...

Brief Summary: This observational study highlights the challenges of managing T1D in 8,004 young children with type 1 diabetes (T1D) (age < 6 years) from 3 international registries: Diabetes Prospective Follow-Up Registry (DPV), T1D Exchange Quality Improvement Network (T1DX-QI), and the Australasian Diabetes Data Network (ADDN), using data collected between 2019 and 2021. More than half of included children did not achieve the recommended HbA1c target < 7.0% (53 mmol/...

Brief summary: The potency of insulin decreases with increasing temperatures. This pilot study compared the concentration and structure of commonly used types of insulin when exposed to high temperatures for prolonged periods of time.Manufacturers are required to provide information on how insulin vials and cartridges should be kept by the patient. These recommendations assume that a working fridge is available and that the medicine can be protected from...